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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKL1
All Species:
17.88
Human Site:
S416
Identified Species:
49.17
UniProt:
Q969V6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q969V6
NP_065882.1
931
98919
S416
A
F
P
A
A
R
L
S
T
G
P
A
L
V
A
Chimpanzee
Pan troglodytes
XP_001146728
1112
120651
T481
V
T
V
A
L
P
V
T
T
L
H
N
T
V
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859224
925
97930
S410
A
F
P
A
A
R
L
S
T
G
P
A
L
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4J6
964
102528
S454
A
F
P
A
A
L
L
S
T
G
S
A
L
V
T
Rat
Rattus norvegicus
Q8R5I7
938
101853
P449
L
P
S
Y
Q
S
S
P
S
G
F
Y
H
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505409
1041
113389
K472
P
F
P
V
A
T
L
K
T
S
A
A
S
S
V
Chicken
Gallus gallus
XP_416243
1105
117878
S550
A
F
P
A
A
R
L
S
T
G
P
A
L
V
T
Frog
Xenopus laevis
Q8AYC2
936
103220
T435
I
V
S
S
S
C
L
T
T
R
E
P
I
K
L
Zebra Danio
Brachydanio rerio
XP_001333839
986
108377
S482
Q
L
P
S
N
T
L
S
S
T
P
P
V
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
N.A.
90
N.A.
82.3
37.6
N.A.
44.1
63.4
46.4
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.4
N.A.
92.6
N.A.
86
52.3
N.A.
55.8
69
58.7
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
N.A.
100
N.A.
80
6.6
N.A.
40
93.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
80
13.3
N.A.
40
93.3
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
56
56
0
0
0
0
0
12
56
0
0
23
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
56
0
0
0
0
0
0
0
0
12
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
56
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% K
% Leu:
12
12
0
0
12
12
78
0
0
12
0
0
45
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
12
12
67
0
0
12
0
12
0
0
45
23
0
0
12
% P
% Gln:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
34
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
23
23
12
12
12
56
23
12
12
0
12
23
0
% S
% Thr:
0
12
0
0
0
23
0
23
78
12
0
0
12
0
34
% T
% Val:
12
12
12
12
0
0
12
0
0
0
0
0
12
56
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _